# Hyperbaric oxygen therapy (HBOT)

Hyperbaric oxygen therapy (HBOT) delivers 100% oxygen at high pressure. The pressure is typically 2.0 to 2.4 times normal atmospheric pressure (the clinical threshold for HBOT is generally at least 1.4 times). You breathe it inside a sealed, pressurized chamber. That sharply raises the oxygen dissolved in your blood plasma. It is an established treatment for three things. They are decompression sickness, carbon monoxide poisoning, and selected non-healing wounds. The off-label longevity uses (for telomere length, cognition, and anti-aging) rest on small trials with weak methods. Current evidence does not support routine use for healthy aging.

## Sources

- Hachmo Y, Hadanny A, Abu Hamed R, et al.. (2020). Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells: a prospective trial. Aging (Albany NY). https://doi.org/10.18632/aging.202188

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_Canonical: https://longevity-switzerland.com/en/glossary/hyperbaric-oxygen-therapy · Part of Longevity Cities · Updated 2026-06-22_