# Astaxanthin May Protect Aging Brains and Livers by Calming Oxidative Stress

*Nrf2/Bach1-ARE pathway are involved in the ameliorative effects of astaxanthin on D-galactose-induced liver and brain aging and injury.*

- **Evidence Level**: Preliminary
- **Publication Types**: Journal Article
- **Journal**: Scientific reports
- **Sample Size**: Aged rats (number not specified)
- **Authors**: Zhang P, Zhang X, Ma S, Jiang M, Zhao W
- **Published**: 2026-05-23
- **Topics**: astaxanthin, antioxidants, brain aging
- **DOI**: https://doi.org/10.1038/s41598-026-52939-0
- **Original Source**: https://pubmed.ncbi.nlm.nih.gov/42177227/

## Summary

In rats given a chemical that speeds up aging, astaxanthin (the red pigment in salmon and shrimp) reduced damage to the brain and liver. It worked about as well as vitamin E and improved memory in the water maze test. The benefits disappeared when researchers blocked a specific antioxidant pathway, confirming how it works.

## Practical Takeaway

This animal study suggests astaxanthin may support brain and liver health by boosting the body's antioxidant defenses.

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_Canonical: https://longevity-switzerland.com/en/research/astaxanthin-may-protect-aging-brains-and-livers-by-calming-oxidative-stress · Part of Longevity Cities · Updated 2026-05-23_