# NMN Calmed Eye Inflammation and Slowed Blood Vessel Damage in Mice

*Nicotinamide Mononucleotide Attenuates Inflammatory Activation, Choroidal Neovascularization, and Lesion-Associated Remodeling.*

- **Evidence Level**: Preliminary
- **Publication Types**: Journal Article
- **Journal**: Investigative ophthalmology & visual science
- **Sample Size**: C57BL/6J mice plus cell experiments
- **Authors**: Wang J, Osada H, Chen S, Yamaguchi S, Hayashi K, Negishi K, Kurihara T, Ban N
- **Published**: 2026-08-03
- **Topics**: NMN, eye health, inflammation
- **DOI**: https://doi.org/10.1167/iovs.67.10.59
- **Original Source**: https://pubmed.ncbi.nlm.nih.gov/42640154/

## Summary

Wet macular degeneration happens when abnormal blood vessels grow under the retina and scar tissue forms. In mice with laser-induced damage mimicking this, NMN shrank the abnormal vessel growth and cut inflammation. It also reduced the scarring that drives late-stage vision loss. This is early animal work, so it says nothing yet about NMN supplements and human eyesight.

## Practical Takeaway

This early animal study suggests NMN may deserve testing for age-related eye disease.

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_Canonical: https://longevity-germany.com/en/research/nmn-calmed-eye-inflammation-and-slowed-blood-vessel-damage-in-mice · Part of Longevity Cities · Updated 2026-08-03_