# Strength Training May Reshape Brain Markers in Older Adults With Early Alzheimer's Signs

- **Evidence Level**: Preliminary
- **Journal**: Age and ageing
- **Sample Size**: 90 cognitively healthy older adults, mean age 72, 58% female
- **Published**: 2026-04-04
- **Topics**: Alzheimer's, exercise, brain health
- **Original Source**: https://pubmed.ncbi.nlm.nih.gov/41967036/

## Summary

A 24-week strength training program altered Alzheimer's-related brain signatures in cognitively healthy older adults. The effect was strongest in participants who already had amyloid buildup in their brains. Those reductions in brain thickness markers were linked to better executive function, suggesting the changes were adaptive rather than harmful. This was a small trial of 90 people around age 72, so the results need replication.

## Practical Takeaway

This study suggests resistance training may support brain health in those with early amyloid buildup.

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