What is the Longevity Research Library?

The Longevity Switzerland Research Library curates recent peer-reviewed studies on longevity, nutrition, exercise, sleep, and supplements. Each study is rated by evidence strength: Strong, Moderate, or Preliminary.

How are evidence levels determined?

Evidence levels are based on study type (meta-analysis, RCT, cohort study), sample size, journal impact factor, and reproducibility of findings.

69 studies

Research Library

Peer-reviewed papers from top journals, summarized and graded by evidence strength. Updated Mon, Wed & Fri.

8/69

Last week

Better Diet Linked to Slower Epigenetic Aging, But Exercise Steals the Show

In two large U.S. studies of older adults, eating a higher-quality diet was tied to slower epigenetic aging and lower death risk. About 44% of the diet-mortality link was explained by GrimAge, a biological aging clock. But when researchers accounted for physical activity, the diet effect mostly disappeared. Movement may matter as much as the menu.

Aging cell·Moderate·May 1, 2026

Mar 15–21, 2026

Anti-Inflammatory Foods May Lower Frailty Risk as You Age

Certain blood metabolites tied to fruits, vegetables, nuts, and legumes were linked to lower frailty risk in nearly 10,000 Canadian adults aged 45-85. The protective effect worked partly by reducing inflammation markers. On the flip side, a high omega-6 to omega-3 ratio and processed meat metabolites were tied to higher frailty risk through increased inflammation. The study tracked participants over three years, connecting dietary patterns to measurable metabolic changes.

npj aging·Moderate·Mar 23, 2026

Resistance Training Plus Amino Acids Beat Either Alone for Muscle in Older Women

In healthy women aged 65 and older, combining resistance exercise with essential amino acid supplements for 12 weeks increased muscle mass more than doing either one alone. The combo group also showed the biggest improvements in fitness tests and the best shift in muscle-related hormones. Inflammatory markers dropped too, with one key marker only declining in the combined group. Each intervention helped on its own, but pairing them produced clearly stronger results.

Journal of the International Society of Sports Nutrition·Moderate·Mar 21, 2026

Undernutrition Linked to Faster Cognitive Decline in Older Adults

Older Italians who were undernourished at the start of the study were much more likely to fall into the steepest cognitive decline group over nine years. About 27% of fast decliners were undernourished, versus 12% of those who stayed sharp. The link was strongest for visible signs like low body weight or muscle loss. Cause and effect run both ways here, since cognitive decline can also reduce eating.

Nutrition (Burbank, Los Angeles County, Calif.)·Moderate·Mar 19, 2026

How Excess Fructose May Damage Far More Than Just Your Liver

This review pulls together evidence showing fructose does more than add calories. It triggers a chain reaction: uric acid buildup, mitochondrial stress, and fat storage signals that affect the liver, kidneys, pancreas, gut, heart, lungs, and brain. The damage traces back to how fructose is processed differently than glucose, depleting cellular energy and driving inflammation. Animal and human studies both point to fructose overload as a metabolic disruptor across nearly every organ system.

Frontiers in bioscience (Elite edition)·Moderate·Mar 17, 2026

Mar 8–14, 2026

Caloric Restriction Slows Aging Most in the Heart and Metabolism

Cutting calories doesn't slow aging evenly across all organs. In a two-year trial, 185 adults were randomly assigned to caloric restriction or normal eating. The caloric restriction group aged about one year less in their cardiovascular and metabolic systems over 24 months. Kidney aging, however, didn't budge, and liver aging only slowed modestly at the two-year mark.

Clinical nutrition (Edinburgh, Scotland)·Strong·Mar 14, 2026

Mar 1–7, 2026

Mediterranean Diet Linked to Lower Death Risk Across 1.8 Million People

Pooling 54 studies with over 1.8 million participants, each one-point bump on a Mediterranean diet score was linked to a 4% lower risk of dying from any cause. The studies covered diverse populations worldwide, with follow-up periods ranging from 2 to 60 years. Evidence certainty was rated moderate, meaning the association is fairly reliable but not ironclad.

Nutrition (Burbank, Los Angeles County, Calif.)·Strong·Mar 4, 2026

Feb 22–28, 2026

Fish-Eaters and Vegetarians Show Slower Biological Aging Than Regular Meat-Eaters

Among over 400,000 UK adults, people who ate fish but little meat aged the slowest biologically. Vegetarians came in a close second. Regular meat-eaters aged fastest by two different biological age measures. These patterns held up over time too. People who stuck with low-meat, fish-based, or vegetarian diets saw their biological aging slow down compared to consistent meat-eaters during follow-up.

Clinical nutrition (Edinburgh, Scotland)·Moderate·Feb 24, 2026

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.

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