What is the Longevity Research Library?

The Longevity Switzerland Research Library curates recent peer-reviewed studies on longevity, nutrition, exercise, sleep, and supplements. Each study is rated by evidence strength: Strong, Moderate, or Preliminary.

How are evidence levels determined?

Evidence levels are based on study type (meta-analysis, RCT, cohort study), sample size, journal impact factor, and reproducibility of findings.

56 studies

Research Library

Peer-reviewed papers from top journals, summarized and graded by evidence strength. Updated Mon, Wed & Fri.

8/56

Apr 12–18, 2026

Healthy Lifestyle Didn't Change Brain Scans, But Still Helped At-Risk Seniors

In older adults at risk for cognitive decline, a two-year program of exercise, better diet, and social engagement didn't visibly change brain biomarkers like amyloid or shrinkage. But people who started with smaller hippocampi (the brain's memory hub) got more cognitive benefit from the structured version. So the lifestyle changes may help thinking even without obviously reshaping the brain.

JAMA neurology·Strong·Apr 19, 2026

Apr 5–11, 2026

Eating More Fruits, Fish, Nuts, and Dairy Tied to Slower Cognitive Decline

In over 3,000 Chinese older adults tracked for about five years, those who ate more from six protective food groups (fruits, vegetables, nuts, legumes, fish, and dairy) showed slower cognitive decline. People scoring highest on this diet scale declined about 0.42 points per year slower on a cognitive test compared to those scoring lowest. The effect was modest but consistent across different ways of measuring cognition.

NPJ science of food·Moderate·Apr 8, 2026

Mar 29 – Apr 4, 2026

Structured Lifestyle Programs Cut Frailty More Than DIY Approaches

A two-year trial compared two lifestyle programs, both involving exercise, diet, social activity, and health monitoring, in over 2,000 older adults at risk for cognitive decline. The structured version (with more accountability and intensity) reduced a frailty index nearly three times more than the self-guided version. This benefit held across age groups, sexes, and body weights. Interestingly though, the frailty improvements didn't explain the cognitive benefits of the structured program, suggesting separate mechanisms.

The journals of gerontology. Series A, Biological sciences and medical sciences·Strong·Apr 5, 2026

For Older Adults With Obesity, Diet Plus Exercise Plus Coaching Beats Any Single Fix

Combining calorie restriction, exercise, and behavioral coaching improved physical function in older adults with obesity more than any single approach alone. That triple combo also reduced body fat without significantly cutting lean mass or bone density. The physical function finding had high-certainty evidence, while body composition results were less certain. Data on quality of life and psychological outcomes were too limited to draw conclusions.

Obesity reviews : an official journal of the International Association for the Study of Obesity·Strong·Apr 2, 2026

Mar 15–21, 2026

Anti-Inflammatory Foods May Lower Frailty Risk as You Age

Certain blood metabolites tied to fruits, vegetables, nuts, and legumes were linked to lower frailty risk in nearly 10,000 Canadian adults aged 45-85. The protective effect worked partly by reducing inflammation markers. On the flip side, a high omega-6 to omega-3 ratio and processed meat metabolites were tied to higher frailty risk through increased inflammation. The study tracked participants over three years, connecting dietary patterns to measurable metabolic changes.

npj aging·Moderate·Mar 22, 2026

Mar 1–7, 2026

Mediterranean Diet Linked to Lower Death Risk Across 1.8 Million People

Pooling 54 studies with over 1.8 million participants, each one-point bump on a Mediterranean diet score was linked to a 4% lower risk of dying from any cause. The studies covered diverse populations worldwide, with follow-up periods ranging from 2 to 60 years. Evidence certainty was rated moderate, meaning the association is fairly reliable but not ironclad.

Nutrition (Burbank, Los Angeles County, Calif.)·Strong·Mar 3, 2026

Feb 22–28, 2026

Sticking With Mediterranean or MIND Diets Linked to Lower Dementia Risk

Following a Mediterranean or MIND diet long-term was linked to meaningful reductions in dementia risk in a study of over 130,000 U.S. nurses and health professionals. Those with the highest Mediterranean diet scores had 21% lower dementia risk, while top MIND diet followers had 14% lower risk. Higher adherence was also tied to 0.75 to 1.59 fewer years of cognitive aging and roughly 40% lower risk of self-reported cognitive decline. Even people who improved their diet over 4 or 8 years saw similar benefits.

Alzheimer's & dementia : the journal of the Alzheimer's Association·Strong·Feb 28, 2026

Fish-Eaters and Vegetarians Show Slower Biological Aging Than Regular Meat-Eaters

Among over 400,000 UK adults, people who ate fish but little meat aged the slowest biologically. Vegetarians came in a close second. Regular meat-eaters aged fastest by two different biological age measures. These patterns held up over time too. People who stuck with low-meat, fish-based, or vegetarian diets saw their biological aging slow down compared to consistent meat-eaters during follow-up.

Clinical nutrition (Edinburgh, Scotland)·Moderate·Feb 23, 2026

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.

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