How a Cellular Calcium Glitch Speeds Up Aging in Mice
Graded Moderate — lifespan study in progeroid and naturally aged mice with mechanistic work in human cells, yet the drug's effect on aging has not been tested in people.
This study suggests calcium balance inside cells may be a future target for aging research.
When cells lose control of their calcium balance, it sets off a chain reaction that triggers DNA damage and inflammation tied to aging. In mice, an old antidepressant called mianserin calmed this calcium chaos. It improved several signs of aging and lengthened their lives. This points to calcium control as a possible target for slowing aging.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.