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Journal ArticleCell communication and signaling : CCS·Jun 2026

How a Common Chemo Drug Eats Away at Muscle, and a Possible Way to Block It

Cisplatin is a widely used cancer drug, but it often wastes away muscle. In mice, scientists found that an immune signaling pathway called cGAS-STING drives much of this muscle loss. Switching off this pathway in muscle helped protect it from the drug's damage. This points to a possible target for keeping muscle intact during chemo.

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.