Skip to content
Journal ArticleReviewCells·Apr 2026

How an Aging Immune System May Drive Alzheimer's and Parkinson's

Key Insight

This review suggests strategies that lower chronic inflammation may help protect the aging brain.


As we age, the immune system gets sloppy and starts running a low-grade inflammation in the background (called inflammaging). This review argues that aging immune cells in the brain lose their protective role and instead fuel diseases like Alzheimer's and Parkinson's. Researchers are exploring senolytics and microbiome therapies to calm this chronic inflammation. It's a reminder that brain aging and immune aging are deeply linked.

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.