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Imaging & diagnostics

Skin imaging / total body photography and dermoscopy

DEHautbildgebung – Ganzkörperfotografie und Dermatoskopie

Dermoscopy (also called dermatoscopy) uses a handheld lens at about 10x magnification. With polarized or immersion light, it reveals pigment patterns and tiny blood vessels under your skin that the naked eye misses. In clinical studies, a meta-analysis found it improves the odds of spotting melanoma by roughly 9 to 15 times versus naked-eye checks. Total body photography (TBP) takes a standardized baseline of all your moles. Combined with repeat digital dermoscopy over time, it helps watch high-risk people. Those include people with more than 50 atypical moles, a family melanoma syndrome, or a past melanoma. AI tools (FotoFinder, SkinVision, MoleScope) and neural networks have matched dermatologists' sensitivity in research. But their real-world performance varies. The method is non-invasive and radiation-free. It has limits, though. It needs trained operators. It is less accurate on pigment-free lesions and on nails, palms, and soles. And there is an unsettled trade-off between catching cancers earlier and doing too many biopsies.

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Sources

  1. Vestergaard ME, Macaskill P, Holt PE, Menzies SW. (2008). Dermoscopy compared with naked eye examination for the diagnosis of primary melanoma: a meta-analysis of studies performed in a clinical setting. *British Journal of Dermatology*doi:10.1111/j.1365-2133.2008.08713.x
  2. Dinnes J, Deeks JJ, Chuchu N, et al.. (2018). Dermoscopy, with and without visual inspection, for diagnosing melanoma in adults. *Cochrane Database of Systematic Reviews*doi:10.1002/14651858.CD011902.pub2
  3. Esteva A, Kuprel B, Novoa RA, et al.. (2017). Dermatologist-level classification of skin cancer with deep neural networks. *Nature*doi:10.1038/nature21056