Exercise Linked to Younger Biological Age, But Effect Is Modest
This study suggests staying physically active may be associated with a slightly younger biological age on certain epigenetic clocks.
Pulling together 44 studies on nearly 145,000 people, researchers found that more physical activity is tied to a younger biological age, but only on certain epigenetic clocks. The effect showed up clearly on GrimAge and Horvath clocks, but not on Hannum or PhenoAge. The size of the benefit was small, and most data came from snapshot studies, so we can't say exercise actually causes the slowdown yet.
Conflict of Interest Disclosure: One author co-founded a longevity medicine clinic and sits on biomarker and longevity boards. Other authors report no conflicts.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.
Related Studies
All researchWhy Your Muscles Need This Enzyme to Reap the Benefits of Exercise
In mice and humans, a muscle enzyme called NOX4 drops as we age.
Staying Active From Midlife Cuts Sarcopenia Risk by Up to 78%
In Norwegians tracked for over 30 years, those who stayed active from middle age into their 70s had 78% lower odds of confirmed muscle loss.
Two Hours of Weekly Strength Training Hits the Sweet Spot for Longevity
In nearly 150,000 adults tracked for up to 30 years, doing 90 to 119 minutes of strength training per week was linked to a 13% lower risk…
