56 Studien

Forschungsbibliothek

Peer-reviewed Papers aus Top-Journals, zusammengefasst und nach Evidenzstärke bewertet. Updates jeden Mo, Mi & Fr.

17/56

Letzte Woche

2

12.–18. Apr 2026

2

29. März – 4. Apr., 2026

6

Structured Lifestyle Programs Cut Frailty More Than DIY Approaches

A two-year trial compared two lifestyle programs, both involving exercise, diet, social activity, and health monitoring, in over 2,000 older adults at risk for cognitive decline. The structured version (with more accountability and intensity) reduced a frailty index nearly three times more than the self-guided version. This benefit held across age groups, sexes, and body weights. Interestingly though, the frailty improvements didn't explain the cognitive benefits of the structured program, suggesting separate mechanisms.

The journals of gerontology. Series A, Biological sciences and medical sciences·Stark·5. Apr. 2026

Exercise Helps Older Adults With Sarcopenic Obesity, but Evidence Quality Is Mixed

Pooling 20 trials of older adults with sarcopenic obesity (low muscle plus excess fat), exercise reduced body fat, BMI, and LDL cholesterol while boosting muscle mass, grip strength, and walking speed. Resistance training stood out for building muscle and strength. Combined training (resistance plus cardio) improved the broadest range of outcomes. However, the authors caution that evidence quality was only moderate for body composition and low for metabolic benefits.

Maturitas·Moderat·5. Apr. 2026

Strength Training May Reshape Brain Markers in Older Adults With Early Alzheimer's Signs

A 24-week strength training program altered Alzheimer's-related brain signatures in cognitively healthy older adults. The effect was strongest in participants who already had amyloid buildup in their brains. Those reductions in brain thickness markers were linked to better executive function, suggesting the changes were adaptive rather than harmful. This was a small trial of 90 people around age 72, so the results need replication.

Age and ageing·Vorläufig·3. Apr. 2026

For Older Adults With Obesity, Diet Plus Exercise Plus Coaching Beats Any Single Fix

Combining calorie restriction, exercise, and behavioral coaching improved physical function in older adults with obesity more than any single approach alone. That triple combo also reduced body fat without significantly cutting lean mass or bone density. The physical function finding had high-certainty evidence, while body composition results were less certain. Data on quality of life and psychological outcomes were too limited to draw conclusions.

Obesity reviews : an official journal of the International Association for the Study of Obesity·Stark·2. Apr. 2026

Balance and Strength Training Together May Best Prevent Falls in Older Adults

A review of 69 trials found that combining gait/balance training with strength exercises reduced both fall risk and fall-related injuries in older adults. Home environment modifications also stood out for reducing fracture risk. Some surprising findings: traditional health education and medication management, as individual components, were actually linked to higher fall and fracture risk. The most effective overall package combined risk assessment, advice, exercise, and environmental changes.

Worldviews on evidence-based nursing·Stark·31. März 2026

NMN Plus Apigenin May Protect Aging Muscle and Bone Better Together

In aged mice, combining the NAD booster NMN with apigenin (a compound found in parsley and chamomile) reduced cartilage breakdown, bone loss, and muscle wasting. The combo works by both producing more NAD+ and blocking enzymes that consume it. Treated mice also showed better exercise capacity. The benefits appeared to work through SIRT3 activation and changes in gut bacteria that produce a helpful fat molecule.

Aging cell·Vorläufig·31. März 2026

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